Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988666 | 0.87 | OPRM1 (0.41) | — | |
| SCHEMBL23365196 | 0.82 | OPRM1 (0.39) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28398405 | 0.80 | ALDH1A1 (0.40) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL23730076 | 0.78 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2GAAKDM4EMAPK1 | |
| SCHEMBL22290800 | 0.76 | DGAT1 (0.38) | ALDH1A1PDE4DSMN1; SMN2KDM4E | |
| SCHEMBL348542 | 0.76 | ALDH1A1 (0.49) | LMNAMEN1KMT2ATHRBALDH1A1 | |
| SCHEMBL23365085 | 0.73 | KDM4E (0.49) | MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5700005 | 0.73 | SMN1; SMN2 (0.50) | ESR1ATMLMNAMEN1KMT2A | |
| SCHEMBL29284164 | 0.72 | KDM4E (0.43) | LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29284906 | 0.72 | DGAT1 (0.36) | ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097096-A2 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |