Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.39 |
| ▸ | CA2 | P00918 | 8/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779373 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL10347081 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL16007385 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL16007211 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL1479612 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL1479487 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL10546836 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL7781968 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL1479485 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C | |
| SCHEMBL7781970 | 0.92 | NAAA (0.48) | NAAAEPHX1TSHRNOD1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12251457-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2025-03-18 | — | — | US | claimed |
| US-20230092150-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | INOLEX INVESTMENT CORPORATION | 2023-03-23 | — | — | US | claimed |
| US-11540991-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2023-01-03 | — | — | US | claimed |
| US-20250186322-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | INOLEX INVESTMENT CORP (US) | 2025-06-12 | — | — | US | disclosed |
| CN-113677337-B | Cationic compositions based on self-neutralizing amino acids | 伊诺莱克斯投资公司 | 2025-05-23 | — | — | CN | disclosed |
| US-12251457-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2025-03-18 | — | — | US | disclosed |
| US-20230092150-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | INOLEX INVESTMENT CORPORATION | 2023-03-23 | — | — | US | disclosed |
| US-11540991-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12251457-B2 | Self-neutralizing amino acid based cationic compositions | SLC6A15, SLC1A5, SLC6A19 | NAAA 31/4885TP53 2069/4885EPHX1 2990/4885 |
| US-20250186322-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | SLC43A1, SLC1A5, SLC7A1 | NAAA 310/4885TP53 1869/4885EPHX1 4346/4885 |
| US-20230092150-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | SLC6A15, SLC1A5, SLC6A19 | NAAA 31/4885TP53 2069/4885EPHX1 2990/4885 |
| US-11540991-B2 | Self-neutralizing amino acid based cationic compositions | SLC6A15, SLC1A5, SLC6A19 | NAAA 31/4885TP53 2069/4885EPHX1 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.