Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27168896 | 0.81 | TSHR (0.39) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL30764632 | 0.81 | TSHR (0.39) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL30059781 | 0.80 | ALDH1A1 (0.38) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL27168855 | 0.80 | ALDH1A1 (0.38) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL27168853 | 0.77 | KDM4E (0.40) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL30764481 | 0.71 | TSHR (0.39) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL13925351 | 0.64 | TSHR (0.42) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL27168890 | 0.64 | TSHR (0.35) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL30764525 | 0.64 | TSHR (0.35) | TSHRCYP1A2HSD17B10ALDH1A1HTT | |
| SCHEMBL30646130 | 0.63 | SRC (0.38) | TSHRCYP1A2HSD17B10ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337290-A | Tri-ring ubiquitin-specific protease 1 inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117263944-A | Ubiquitin-specific protease 1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2022233263-A1 | TRICYCLIC UBIQUITIN SPECIFIC PROTEASE 1 INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2022-11-10 | — | — | WO | disclosed |