Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781741 | 0.77 | TSHR (0.46) | TSHRKDM4EDRD1ALDH1A1LMNA | |
| SCHEMBL18237942 | 0.76 | TSHR (0.39) | TSHRKDM4EDRD1ALDH1A1LMNA | |
| SCHEMBL27168896 | 0.72 | TSHR (0.39) | TSHRKDM4ELRRK2ALDH1A1POLB | |
| SCHEMBL30764632 | 0.72 | TSHR (0.39) | TSHRKDM4ELRRK2ALDH1A1POLB | |
| SCHEMBL19131345 | 0.72 | TSHR (0.39) | TSHRKDM4EALDH1A1HSD17B10GABRG2 | |
| SCHEMBL27168855 | 0.71 | ALDH1A1 (0.38) | TSHRKDM4EALDH1A1POLBRXFP1 | |
| SCHEMBL30059797 | 0.71 | TSHR (0.38) | TSHRKDM4EALDH1A1POLBRXFP1 | |
| SCHEMBL30059781 | 0.71 | ALDH1A1 (0.38) | TSHRKDM4EALDH1A1POLBRXFP1 | |
| SCHEMBL30764609 | 0.69 | ALDH1A1 (0.39) | TSHRKDM4EALDH1A1GRM5MAPT | |
| SCHEMBL27168853 | 0.68 | KDM4E (0.40) | TSHRKDM4EALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337290-A | Tri-ring ubiquitin-specific protease 1 inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |