Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30059797 | 0.81 | TSHR (0.38) | TSHRCYP1A2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL30059781 | 0.81 | ALDH1A1 (0.38) | TSHRCYP1A2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL30764525 | 0.78 | TSHR (0.35) | TSHRCYP1A2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL30764481 | 0.72 | TSHR (0.39) | TSHRCYP1A2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL2483863 | 0.68 | SMN1; SMN2 (0.49) | TSHRHSD17B10ALDH1A1KMT2AHTT | |
| SCHEMBL2708822 | 0.66 | ATM (0.35) | KMT2AKDM4EGAA | |
| SCHEMBL30642330 | 0.64 | SMN1; SMN2 (0.46) | TSHRHSD17B10ALDH1A1KMT2AHTT | |
| SCHEMBL13482117 | 0.64 | SMN1; SMN2 (0.46) | TSHRHSD17B10ALDH1A1KMT2AHTT | |
| SCHEMBL21404168 | 0.63 | ALDH1A1 (0.41) | CYP1A2HSD17B10ALDH1A1KMT2AKDM4E | |
| SCHEMBL30632015 | 0.63 | ALDH1A1 (0.41) | CYP1A2HSD17B10ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337290-A | Tri-ring ubiquitin-specific protease 1 inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |