Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 11/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30060423 | 0.78 | CNR2 (0.52) | CNR1CNR2ACHE | |
| SCHEMBL21000228 | 0.70 | DDB1 (0.49) | DDB1CRBNSCN9AALDH1A1 | |
| SCHEMBL5665856 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL20741057 | 0.70 | GRM4 (0.63) | GRM4 | |
| SCHEMBL20741060 | 0.70 | GRM4 (0.63) | GRM4 | |
| SCHEMBL30057426 | 0.69 | ATM (0.37) | CNR1CNR2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8043123 | 0.69 | CNR2 (0.74) | CNR1CNR2ACHEALDH1A1HPGD | |
| SCHEMBL3340760 | 0.69 | ADORA2A (0.59) | DDB1CRBNLSSGRM4ALDH1A1 | |
| SCHEMBL7822340 | 0.69 | CNR2 (0.53) | CNR1CNR2ACHE | |
| SCHEMBL8001275 | 0.68 | TTR (0.38) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253252-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |