Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.52 |
| ▸ | CNR1 | P21554 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22151030 | 0.79 | L3MBTL1 (0.48) | CNR2CNR1ACHEL3MBTL1HTT | |
| SCHEMBL30059893 | 0.78 | DDB1 (0.39) | CNR2CNR1ACHE | |
| SCHEMBL7119708 | 0.74 | CNR2 (0.69) | CNR2CNR1ACHEL3MBTL1MAPT | |
| SCHEMBL3380500 | 0.73 | L3MBTL1 (0.52) | CNR2L3MBTL1HTTTDP1MAPT | |
| SCHEMBL13106375 | 0.72 | L3MBTL1 (0.49) | CNR2CNR1ACHEL3MBTL1HTT | |
| SCHEMBL8000556 | 0.72 | HTR1A (0.43) | L3MBTL1HTR1ACYP2C19HTTPOLB | |
| SCHEMBL7998670 | 0.72 | MAPT (0.40) | L3MBTL1HTR1AHTTPOLBTDP1 | |
| SCHEMBL7815982 | 0.72 | CNR2 (0.57) | CNR2CNR1ACHEL3MBTL1HTR1A | |
| SCHEMBL30955734 | 0.72 | L3MBTL1 (0.51) | CNR2L3MBTL1HTTTDP1MAPT | |
| SCHEMBL19586107 | 0.72 | L3MBTL1 (0.51) | CNR2CNR1ACHEL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253252-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |