Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31668345 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL18674939 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL17267076 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL18662748 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL17267123 | 0.95 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL18675078 | 0.94 | ACSS2 (0.88) | ACSS2 | |
| SCHEMBL18674897 | 0.93 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL29917914 | 0.93 | ACSS2 (0.87) | ACSS2 | |
| SCHEMBL18675062 | 0.92 | ACSS2 (0.86) | ACSS2 | |
| SCHEMBL18675072 | 0.92 | ACSS2 (1.00) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335371-B | Tetrazole derivatives | 默克专利股份公司 | 2024-12-27 | — | — | CN | disclosed |
| EP-4121423-A1 | TETRAZOLE DERIVATIVES | Merck Patent GmbH (DE) | 2023-01-25 | — | — | EP | disclosed |
| EP-4121429-A1 | CONDENSED PYRIDINE DERIVASTIVES SUBSTITUED BY AMIDE FUNCTIONS AS ACSS2 INHIBITORS | Merck Patent GmbH (DE) | 2023-01-25 | — | — | EP | disclosed |
| CN-115443275-A | Condensed pyridine derivatives substituted with amide functions as ACSS2 inhibitors | 默克专利股份公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115335371-A | Tetrazole derivatives | 默克专利股份公司 | 2022-11-11 | — | — | CN | disclosed |