Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30060694 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL18674939 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL17267076 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL18662748 | 1.00 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL17267123 | 0.95 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL18675078 | 0.94 | ACSS2 (0.88) | ACSS2 | |
| SCHEMBL18674897 | 0.93 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL29917914 | 0.93 | ACSS2 (0.87) | ACSS2 | |
| SCHEMBL18675062 | 0.92 | ACSS2 (0.86) | ACSS2 | |
| SCHEMBL18675072 | 0.92 | ACSS2 (1.00) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243168-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | THE WISTAR INST (US) | 2025-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243168-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | ACSS2, ACACB, ACACA | ACSS2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.