Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546450 | 1.00 | ALDH1A1 (0.64) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL16054038 | 0.96 | ALDH1A1 (0.59) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL27985029 | 0.87 | CTSB (0.60) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL29710198 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL27087824 | 0.87 | ALDH1A1 (0.68) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL6609562 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL21600747 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL14941460 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL5238095 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTKCNJ1LMNASMN1; SMN2 | |
| SCHEMBL16054847 | 0.84 | L3MBTL1 (0.61) | ALDH1A1MAPTSMN1; SMN2HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-B | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-112047932-B | Pyrazole spleen tyrosine kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-11-08 | — | — | CN | disclosed |