SCHEMBL30063005

SCHEMBL30063005

CCOC(=O)C1NC(=O)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
HIF1A Q16665 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
TP53 P04637 2/20 0.37
ALDH1A1 P00352 6/20 0.37
HTT P42858 3/20 0.37
KDM4E B2RXH2 4/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 3/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 3/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21176305 0.94 MEN1 (0.37) MAPTHIF1AMEN1KMT2ACYP1A2
SCHEMBL28875903 0.89 MAPT (0.35) MAPTHIF1AMEN1KMT2ACYP1A2
SCHEMBL31552080 0.82 ALDH1A1 (0.38) MAPTHIF1AMEN1KMT2ACYP1A2
SCHEMBL21183544 0.81 KMT2A (0.42) MAPTHIF1AKMT2ACYP1A2ALDH1A1
SCHEMBL3939441 0.74 HTT (0.38) MAPTCYP2C19HTTKDM4ELMNA
SCHEMBL7271734 0.74 HTT (0.38) MAPTCYP2C19HTTKDM4ELMNA
SCHEMBL27096455 0.70 DDB1 (0.38) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL6506166 0.69 KDM4E (0.45) MAPTMEN1KMT2ACYP1A2CYP2D6
SCHEMBL5204219 0.69 LMNA (0.40) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL29008067 0.69 LMNA (0.40) MAPTMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C MAPT 4673/4885HIF1A 2674/4885MEN1 4361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.