Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475292 | 0.92 | NMBR (0.40) | SIRT2NMBRREN | |
| SCHEMBL31094172 | 0.88 | NMBR (0.38) | SIRT2NMBRRENKLK7 | |
| SCHEMBL31094168 | 0.86 | REN (0.38) | SIRT2NMBRRENACE | |
| SCHEMBL30782930 | 0.83 | ACE (0.40) | SIRT2ACE | |
| SCHEMBL30107538 | 0.82 | SIRT2 (0.44) | SIRT2NMBRREN | |
| SCHEMBL29549611 | 0.82 | SIRT2 (0.37) | SIRT2NMBR | |
| SCHEMBL9959535 | 0.81 | SIRT2 (0.53) | SIRT2NMBRACEPPARGPPARD | |
| SCHEMBL5349888 | 0.81 | SIRT2 (0.53) | SIRT2NMBRACEPPARGPPARD | |
| SCHEMBL29401183 | 0.81 | SIRT2 (0.53) | SIRT2NMBRACEPPARGPPARD | |
| SCHEMBL30384919 | 0.80 | SIRT2 (0.44) | SIRT2NMBRACEKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501871-B | Method for preparing darunavagon by combining solid phase with liquid phase | 汉肽生物医药集团有限公司 | 2022-10-28 | — | — | CN | disclosed |