SCHEMBL29475292

SCHEMBL29475292

CC(C)(C)OC[C@H](NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NMBR P28336 1/20 0.40
▸ SIRT2 Q8IXJ6 12/20 0.38
▸ REN P00797 1/20 0.37
▸ CTSS P25774 2/20 0.36
▸ CTSL P07711 1/20 0.36
▸ CTSB P07858 1/20 0.36
▸ CTSK P43235 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30065645 0.92 SIRT2 (0.40) NMBRSIRT2REN
SCHEMBL29549611 0.90 SIRT2 (0.37) NMBRSIRT2
SCHEMBL31094172 0.90 NMBR (0.38) NMBRSIRT2REN
SCHEMBL30641716 0.89 PTPN1 (0.40) NMBRSIRT2
SCHEMBL31094168 0.87 REN (0.38) NMBRSIRT2RENCTSSCTSL
SCHEMBL29427178 0.85 NMBR (0.51) NMBRSIRT2CTSSCTSLCTSB
SCHEMBL29427176 0.85 NMBR (0.51) NMBRSIRT2CTSSCTSLCTSB
SCHEMBL30665993 0.84 NMBR (0.44) NMBRSIRT2CTSSCTSLCTSB
SCHEMBL30277394 0.84 NMBR (0.44) NMBRSIRT2RENCTSS
SCHEMBL30782930 0.82 ACE (0.40) SIRT2CTSSCTSLCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220324936-A1 PROCESS FOR THE MANUFACTURE OF GLUCAGON Fresenius Kabi Ipsum S.R.L. (IT) 2022-10-13 — — US claimed
EP-3986919-A1 PROCESS FOR THE MANUFACTURE OF GLUCAGON Fresenius Kabi iPSUM S.r.l. (IT) 2022-04-27 — — EP claimed
CN-114401981-A Process for producing glucagon 北京费森尤斯卡比医药有限公司 2022-04-26 — — CN claimed
CN-114401981-B Glucagon production method 北京费森尤斯卡比医药有限公司 2024-11-08 — — CN disclosed
CN-115975057-B Solid phase synthesis method of trastuzumab 杭州信海医药科技有限公司 2023-05-16 — — CN disclosed
CN-115975057-B Solid phase synthesis method of trastuzumab 杭州信海医药科技有限公司 2023-05-16 — — CN disclosed
CN-115975057-A Solid-phase synthesis method of clodotoxin 杭州信海医药科技有限公司 2023-04-18 — — CN disclosed
CN-115975057-A Solid-phase synthesis method of clodotoxin 杭州信海医药科技有限公司 2023-04-18 — — CN disclosed
US-20220324936-A1 PROCESS FOR THE MANUFACTURE OF GLUCAGON Fresenius Kabi Ipsum S.R.L. (IT) 2022-10-13 — — US disclosed
EP-3986919-A1 PROCESS FOR THE MANUFACTURE OF GLUCAGON Fresenius Kabi iPSUM S.r.l. (IT) 2022-04-27 — — EP disclosed
CN-114401981-A Process for producing glucagon 北京费森尤斯卡比医药有限公司 2022-04-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324936-A1 PROCESS FOR THE MANUFACTURE OF GLUCAGON IAPP, GCG, GLP1R NMBR 1421/4885SIRT2 4064/4885REN 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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