SCHEMBL30065796

SCHEMBL30065796

COC(=O)c1ccnc(C(=O)OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.62
KDM6B O15054 2/20 0.62
KDM5C P41229 2/20 0.62
KDM4C Q9H3R0 2/20 0.62
KDM2A Q9Y2K7 2/20 0.62
KDM3A Q9Y4C1 2/20 0.62
ALOX15 P16050 3/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
MAPK1 P28482 2/20 0.55
JMJD6 Q6NYC1 1/20 0.54
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.50
HTT P42858 2/20 0.50
KDM5B Q9UGL1 2/20 0.50
TET3 O43151 1/20 0.50
KDM4A O75164 1/20 0.50
BBOX1 O75936 1/20 0.50
KDM5A P29375 1/20 0.50
ASPH Q12797 1/20 0.50
KDM4D Q6B0I6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70350 1.00 KDM4E (0.62) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL30745026 0.89 KDM4E (0.68) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL30779113 0.89 KDM4E (0.68) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL1759313 0.89 KDM4E (0.58) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL30378954 0.89 KDM4E (0.58) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL4939178 0.89 KDM4E (0.50) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL2716237 0.89 KDM4E (0.68) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL475565 0.89 KDM4E (0.68) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL30236802 0.89 KDM4E (0.50) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL1759324 0.87 KDM4E (0.57) KDM4EKDM6BKDM5CKDM4CKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322350-A Degradable bio-based polyester and preparation method and application thereof 苏州瀚海新材料有限公司 2022-11-11 CN claimed
CN-118745147-A Cobalt-catalyzed method for preparing isonicotinic acid compound by taking carbon dioxide as carboxyl source 南开大学 2024-10-08 CN disclosed
CN-115322350-B Degradable bio-based polyester and preparation method and application thereof 苏州瀚海新材料有限公司 2024-04-30 CN disclosed
CN-115322350-A Degradable bio-based polyester and preparation method and application thereof 苏州瀚海新材料有限公司 2022-11-11 CN disclosed