Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | KDM6B | O15054 | 2/20 | 0.68 |
| ▸ | KDM5C | P41229 | 2/20 | 0.68 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.68 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.68 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.67 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.67 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.67 |
| ▸ | TET3 | O43151 | 1/20 | 0.67 |
| ▸ | KDM4A | O75164 | 1/20 | 0.67 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.67 |
| ▸ | KDM5A | P29375 | 1/20 | 0.67 |
| ▸ | ASPH | Q12797 | 1/20 | 0.67 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.67 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.67 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.67 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779113 | 1.00 | KDM4E (0.68) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL70350 | 0.89 | KDM4E (0.62) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL30065796 | 0.89 | KDM4E (0.62) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL30745026 | 0.86 | KDM4E (0.68) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL2716237 | 0.86 | KDM4E (0.68) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL30378954 | 0.86 | KDM4E (0.58) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1759313 | 0.86 | KDM4E (0.58) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL13950719 | 0.84 | KDM4E (0.57) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1759324 | 0.84 | KDM4E (0.57) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL19616007 | 0.83 | KDM4E (0.60) | KDM4EKDM6BKDM5CKDM4CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103788079-A | Preparation method for isonicotinic acid | WUXI VISION PRO LTD | 2014-05-14 | — | — | CN | claimed |
| CN-112707873-B | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| US-11807886-B2 | Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid | BIOME BIOPLASTICS LIMITED (GB) | 2023-11-07 | — | — | US | disclosed |
| US-20230212190-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2023-07-06 | — | — | US | disclosed |
| US-20230212190-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2023-07-06 | — | — | US | disclosed |
| EP-3307901-B1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID | BIOME BIOPLASTICS LTD (GB) | 2022-04-27 | — | — | EP | disclosed |
| US-11059836-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2021-07-13 | — | — | US | disclosed |
| US-20210206963-A1 | COPOLYMER BLENDS | BIOME BIOPLASTICS LIMITED (GB) | 2021-07-08 | — | — | US | disclosed |
| US-10612057-B2 | Process for the preparation of 2,4- or 2,5-pyridinedicarboxylic acid and copolymers derived therefrom | BIOME BIOPLASTICS LIMITED (GB) | 2020-04-07 | — | — | US | disclosed |
| WO-2020035593-A1 | COPOLYMER BLENDS | BIOME BIOPLASTICS LIMITED (GB) | 2020-02-20 | — | — | WO | disclosed |
| US-20070082900-A1 | Methods for inhibiting protein kinases | SCHERING CORPORATION | 2007-04-12 | — | — | US | disclosed |
| US-20070072881-A1 | Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION | 2007-03-29 | — | — | US | disclosed |
| EP-0585328-B1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER (US) | 2002-01-09 | — | — | EP | disclosed |
| US-5852038-A | Substituted 3-aminoquinuclidines | PFIZER INC (US) | 1998-12-22 | — | — | US | disclosed |
| US-5716965-A | Substituted 3-aminoquinuclidines | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0533132-B1 | Process for the oxidation of hydroxymethylpyridine derivatives to pyridine carboxylic acid derivatives | HOECHST AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0585328-A1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5259933-A | Process for oxidizing hydroxymethylpyridine derivatives to pyridinecarboxylic acid derivatives at nickel oxide hydroxide anodes | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| EP-0533132-A1 | Process for the oxidation of hydroxymethylpyridine derivatives to pyridine carboxylic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |
| WO-1992020676-A1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER INC. (US) | 1992-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212190-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | KDM4E 4585/4885KDM6B 4697/4885KDM5C 4770/4885 |
| US-20070082900-A1 | Methods for inhibiting protein kinases | PIM1, AURKC, PIM3 | KDM4E 1092/4885KDM6B 1334/4885KDM5C 762/4885 |
| US-11807886-B2 | Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid | HPD, PGD, PCCA | KDM4E 378/4885KDM6B 647/4885KDM5C 261/4885 |
| US-11059836-B2 | Probes for imaging huntingtin protein | HTT, HYPK, HSPBP1 | KDM4E 4585/4885KDM6B 4697/4885KDM5C 4770/4885 |
| US-10612057-B2 | Process for the preparation of 2,4- or 2,5-pyridinedicarboxylic acid and copolymers derived therefrom | HPD, PCCA, MVD | KDM4E 657/4885KDM6B 484/4885KDM5C 536/4885 |
| US-20070072881-A1 | Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors | CDK2, CDK1, CDKN1A | KDM4E 673/4885KDM6B 864/4885KDM5C 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.