Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | KDM5C | P41229 | 5/20 | 0.68 |
| ▸ | KDM6B | O15054 | 3/20 | 0.68 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.68 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.68 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.68 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.67 |
| ▸ | ALKBH5 | Q6P6C2 | 5/20 | 0.67 |
| ▸ | KDM4A | O75164 | 4/20 | 0.67 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TET3 | O43151 | 1/20 | 0.67 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | KDM5A | P29375 | 1/20 | 0.67 |
| ▸ | ASPH | Q12797 | 1/20 | 0.67 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.67 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.67 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.67 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745026 | 1.00 | KDM4E (0.68) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL70350 | 0.89 | KDM4E (0.62) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL30065796 | 0.89 | KDM4E (0.62) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL30779113 | 0.86 | KDM4E (0.68) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL475565 | 0.86 | KDM4E (0.68) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL4939178 | 0.86 | KDM4E (0.50) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL30236802 | 0.86 | KDM4E (0.50) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL4612998 | 0.85 | FTO (0.71) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL8868177 | 0.84 | ALDH1A1 (0.51) | KDM4EKDM5CKDM6BKDM4CKDM2A | |
| SCHEMBL13545747 | 0.83 | KDM4E (0.53) | KDM4EKDM5CKDM6BKDM4CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2018-05-31 | — | — | US | claimed |
| EP-3307901-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | Biome Bioplastics Limited (GB) | 2018-04-18 | — | — | EP | claimed |
| CN-104363887-B | Compositions, methods and uses comprising pyridine dicarboxylic acid esters and esters of glucose and fatty acids | 莱雅公司 | 2017-11-10 | — | — | CN | claimed |
| CN-107106452-A | Specific pyridinedicarboxylicacid acid derivatives/antioxidant combination | 欧莱雅 | 2017-08-29 | — | — | CN | claimed |
| WO-2016202875-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2016-12-22 | — | — | WO | claimed |
| US-20050171346-A1 | Hexahydropyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and methods of preparation | AVENTIS PHARMA S.A. (FR) | 2005-08-04 | — | — | US | claimed |
| US-20260085336-A1 | NEW POLYMERS AND METHODS | BIOME BIOPLASTICS LTD (GB) | 2026-03-26 | — | — | US | disclosed |
| EP-4663242-A1 | TARGETING THE ENERGY COUPLING FACTOR (ECF) TRANSPORTERS AS NOVEL ANTIMICROBIAL TARGET | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2025-12-17 | — | — | EP | disclosed |
| US-12454710-B2 | Process for the preparation of 2,4- or 2,5-pyridinedicarboxylic acid and copolymers derived therefrom | BIOME BIOPLASTICS LIMITED (GB) | 2025-10-28 | — | — | US | disclosed |
| US-12415793-B2 | Modulators of TMEM16A for treating respiratory disease | TMEM16A LIMITED (GB) | 2025-09-16 | — | — | US | disclosed |
| WO-2025104079-A1 | SALICYLIC ACID AND PICOLINIC ACID DERIVATIVES AS INHIBITORS OF ENERGY COUPLING FACTOR (ECF) TRANSPORTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2025-05-22 | — | — | WO | disclosed |
| US-20240287562-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2024-08-29 | — | — | US | disclosed |
| CN-114269433-B | Modulators of TMEM16A for the treatment of respiratory diseases | TMEM16A有限公司 | 2024-08-02 | — | — | CN | disclosed |
| US-6673799-B1 | INHIBITS BINDING TO ANDROGEN RECEPTOR; ANTIANDROGEN | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1122242-A1 | CYANOPHENYL DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0573467-B1 | NEUROLEPTIC PERHYDRO-1H-PYRIDO 1,2-a]PYRAZINES | PFIZER (US) | 1995-05-31 | — | — | EP | disclosed |
| EP-0573467-A1 | NEUROLEPTIC PERHYDRO-1H-PYRIDO 1,2-a]PYRAZINES. | PFIZER (US) | 1993-12-15 | — | — | EP | disclosed |
| US-5157034-A | Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines | PFIZER INC. (US) | 1992-10-20 | — | — | US | disclosed |
| WO-1992015580-A1 | NEUROLEPTIC PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES | PFIZER INC. (US) | 1992-09-17 | — | — | WO | disclosed |
| CN-1060655-A | 4-or 5-substituted pyridines-2-carboxylic acid, their preparation method and medicinal | HOECHST AG (DE) | 1992-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12415793-B2 | Modulators of TMEM16A for treating respiratory disease | TMEM109, CFTR, TMEM120A | KDM4E 3220/4885KDM5C 4247/4885KDM6B 3222/4885 |
| US-12454710-B2 | Process for the preparation of 2,4- or 2,5-pyridinedicarboxylic acid and copolymers derived therefrom | HPD, PCCA, MVD | KDM4E 657/4885KDM5C 536/4885KDM6B 484/4885 |
| US-20260085336-A1 | NEW POLYMERS AND METHODS | PGD, HPD, UROD | KDM4E 286/4885KDM5C 315/4885KDM6B 269/4885 |
| US-20050171346-A1 | Hexahydropyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and methods of preparation | HEXD, CDK5, CHUK | KDM4E 2612/4885KDM5C 606/4885KDM6B 2412/4885 |
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | HPD, PCCA, MVD | KDM4E 657/4885KDM5C 536/4885KDM6B 484/4885 |
| US-20240287562-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | HPD, PCCA, MVD | KDM4E 631/4885KDM5C 548/4885KDM6B 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.