SCHEMBL30065871

SCHEMBL30065871

COC(=O)NNC(=O)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.54
NR1H4 Q96RI1 1/20 0.54
KMT2A Q03164 5/20 0.50
RAB9A P51151 4/20 0.50
POLB P06746 2/20 0.50
CTDSP1 Q9GZU7 2/20 0.50
GAA P10253 2/20 0.50
HTT P42858 2/20 0.50
LMNA P02545 1/20 0.50
MEN1 O00255 4/20 0.49
NPC1 O15118 4/20 0.49
CA12 O43570 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
KDM4E B2RXH2 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
PKM P14618 1/20 0.47
MAPT P10636 4/20 0.47
ALDH1A1 P00352 2/20 0.47
FAAH O00519 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29191736 0.86 NPC1 (0.59) KMT2ARAB9APOLBGAAHTT
SCHEMBL11540901 0.84 GAA (0.69) EPHX2KMT2ARAB9APOLBCTDSP1
SCHEMBL3001175 0.83 SMN1; SMN2 (0.64) EPHX2NR1H4KMT2ARAB9APOLB
SCHEMBL29191732 0.81 MEN1 (0.60) KMT2ARAB9APOLBGAAHTT
SCHEMBL29191763 0.81 GAA (0.71) KMT2ARAB9APOLBGAALMNA
SCHEMBL4745756 0.79 EPHX2 (0.71) EPHX2NR1H4KMT2ARAB9APOLB
SCHEMBL12369268 0.77 MITF (0.64) KMT2ARAB9APOLBLMNAMEN1
SCHEMBL3885202 0.76 EPHX2 (0.62) EPHX2NR1H4KMT2ARAB9APOLB
SCHEMBL5735649 0.75 EPHX2 (0.45) EPHX2NR1H4KMT2ARAB9APOLB
Urea SCHEMBL4746502 0.74 EPHX2 (0.65) EPHX2NR1H4KMT2ARAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277656-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF (주)스파크바이오파마 2023-01-05 WO disclosed