Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 7/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475655 | 0.89 | POLB (0.45) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL3699913 | 0.84 | IMPDH2 (0.49) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL31445554 | 0.76 | KMT2A (0.44) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL16428549 | 0.76 | POLB (0.49) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL29518610 | 0.74 | POLB (0.66) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL104280 | 0.74 | POLB (0.66) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL8718691 | 0.73 | MAOA (0.53) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL338999 | 0.73 | POLB (0.50) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL9404617 | 0.73 | POLB (0.50) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 | |
| SCHEMBL30934831 | 0.73 | POLB (0.50) | POLBGAAIMPDH2IMPDH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368272-A | Preparation method of 4-cyano-2-methoxybenzaldehyde | 汉瑞药业(荆门)有限公司 | 2022-11-22 | — | — | CN | disclosed |