Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699913 | 0.80 | IMPDH2 (0.49) | KDM4EALDH1A1CA1CA2SMN1; SMN2 | |
| SCHEMBL27475655 | 0.79 | POLB (0.45) | KDM4EALDH1A1TSHRCA1CA2 | |
| SCHEMBL31445485 | 0.78 | RIPK1 (0.38) | KMT2ATSHRSMN1; SMN2MAPK1AKR1C3 | |
| SCHEMBL16267366 | 0.78 | CXCL8 (0.42) | KDM4EALDH1A1SMN1; SMN2MAPK1AKR1C3 | |
| SCHEMBL20534709 | 0.76 | KMT2A (0.47) | KMT2AKDM4ETSHRCA12CA1 | |
| SCHEMBL31446707 | 0.76 | AKR1C3 (0.52) | KMT2AKDM4ECA12CA1CA2 | |
| SCHEMBL31445111 | 0.76 | KMT2A (0.47) | KMT2AKDM4ETSHRCA12CA1 | |
| SCHEMBL30066044 | 0.76 | POLB (0.45) | KDM4EALDH1A1TSHRSMN1; SMN2POLB | |
| SCHEMBL13172191 | 0.73 | AKR1C3 (0.52) | ALDH1A1TSHRAKR1C3AKR1C2PTGS1 | |
| SCHEMBL22980117 | 0.71 | CA12 (0.43) | KMT2AKDM4EALDH1A1TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |