Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 3/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 6/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388585 | 0.87 | TDP2 (0.48) | TDP2NSD2PAX8TDP1ABL1 | |
| Benzoic Acid SCHEMBL1879517 | 0.84 | NAPRT (0.45) | TDP1CES1MEN1BLMKMT2A | |
| Acetic Acid SCHEMBL9604110 | 0.78 | TDP1 (0.42) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL2967094 | 0.77 | TDP2 (0.58) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL32689420 | 0.76 | TDP1 (0.39) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL32689421 | 0.74 | TDP1 (0.38) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL1895059 | 0.73 | TDP1 (0.37) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL31288011 | 0.73 | TDP1 (0.37) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL2961522 | 0.72 | ALDH1A1 (0.39) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL16115792 | 0.71 | ALDH1A1 (0.39) | TDP2NSD2PAX8TDP1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377915-B | Pyrazolo-pyridone compound crystal form D | 鲁南制药集团股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-113710661-A | Compounds and methods for treating cancer | 上海睿跃生物科技有限公司 | 2021-11-26 | — | — | CN | claimed |
| CN-110467601-B | Pyrazole bipyridyl ketone compound, intermediate, preparation method and application thereof | 杭州市西溪医院 | 2021-07-02 | — | — | CN | claimed |
| WO-2020200291-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2020-10-08 | — | — | WO | claimed |
| CN-111377915-A | Pyrazolo-pyridone compound crystal form D | 山东新时代药业有限公司 | 2020-07-07 | — | — | CN | claimed |
| EP-1702013-B1 | INK AND INK SET FOR INKJET RECORDING | FUJIFILM CORP (JP) | 2014-09-10 | — | — | EP | claimed |
| US-7276524-B2 | Pyridyl alkane acid amides as cytostatics and immunosuppressives | ASTELLAS DEUTSCHLAND GMBH (DE) | 2007-10-02 | — | — | US | claimed |
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | ASTELLAS PHARMA GMBH (DE) | 2007-09-20 | — | — | US | claimed |
| US-20070142377-A1 | Pyridyl Alkene and Pyridyl Alkine-Acid Amides as Cytostatics and Immunosuppressives | BIEDERMANN ELFI | 2007-06-21 | — | — | US | claimed |
| EP-1380585-B1 | Pyrazolopyridinone as intermediate | PFIZER PROD INC (US) | 2004-11-10 | — | — | EP | claimed |
| US-5665528-A | INDOLE DERIVATIVE DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-09 | — | — | US | claimed |
| EP-0775938-A1 | Combination of yellow filter dye and 4-equivalent pyrazolone magenta coupler | EASTMAN KODAK COMPANY (US) | 1997-05-28 | — | — | EP | claimed |
| US-5609999-A | INDOLE DYE; STORAGE STABILITY, COLOR REPRODUCIBILITY, SHARPNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1997-03-11 | — | — | US | claimed |
| EP-0430186-B1 | Silver halide photographic light-sensitive materials | FUJI PHOTO FILM CO LTD (JP) | 1995-11-22 | — | — | EP | claimed |
| US-5459026-A | N-phosphonoalkylindole derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-17 | — | — | US | claimed |
| US-5272050-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-21 | — | — | US | claimed |
| US-5213957-A | Oxonol dye with carboxy or sulfonamide group and indale ring | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-25 | — | — | US | claimed |
| EP-0292825-B1 | REACTIVE DYES | BAYER AG (DE) | 1991-08-07 | — | — | EP | claimed |
| EP-0430186-A1 | Silver halide photographic light-sensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0292825-A2 | Reactive dyes | BAYER AG (DE) | 1988-11-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | NFATC1, PDCD1, ACIN1 | TDP2 2335/4885NSD2 3557/4885PAX8 2219/4885 |
| US-20070142377-A1 | Pyridyl Alkene and Pyridyl Alkine-Acid Amides as Cytostatics and Immunosuppressives | ALK, TYMP, PDCD1 | TDP2 2723/4885NSD2 3428/4885PAX8 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.