Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19530936 | 0.88 | ACHE (0.47) | ACHECYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL15280189 | 0.83 | ACHE (0.46) | ACHECYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL30066982 | 0.83 | MTNR1A (0.51) | CYP1A2CYP2C9CYP2C19MAPTERN1 | |
| SCHEMBL10388887 | 0.83 | MTNR1A (0.51) | CYP1A2CYP2C9CYP2C19MAPTERN1 | |
| SCHEMBL812303 | 0.82 | LMNA (0.53) | CYP1A2CYP2C9CYP2C19MAPTERN1 | |
| SCHEMBL15414614 | 0.82 | ERN1 (0.43) | CYP1A2CYP2C9CYP2C19MAPTERN1 | |
| SCHEMBL30067006 | 0.82 | ERN1 (0.59) | CYP1A2CYP2C9CYP2C19MAPTERN1 | |
| SCHEMBL30067092 | 0.82 | ERN1 (0.46) | CYP1A2CYP2C9CYP2C19MAPTERN1 | |
| SCHEMBL3008338 | 0.82 | ERN1 (0.59) | CYP1A2CYP2C9CYP2C19MAPTERN1 | |
| SCHEMBL8989547 | 0.82 | ERN1 (0.46) | CYP1A2CYP2C9CYP2C19MAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116920-A2 | 17BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 INHIBITORS FOR THE TREATMENT OF HORMONE-DEPENDENT DISEASES | Universität des Saarlandes (DE) | 2008-10-02 | — | — | WO | disclosed |