Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30067231 | 0.93 | KMT2A (0.38) | CHRNA7MMP1MEN1MAPTKMT2A | |
| SCHEMBL22709344 | 0.89 | ALDH1A1 (0.37) | CHRNA7MMP1HDAC9LMNAPOLB | |
| SCHEMBL30067472 | 0.88 | MEN1 (0.35) | POLBOPRL1MEN1MAPTKMT2A | |
| SCHEMBL22709350 | 0.86 | NOTUM (0.40) | MMP1HDAC9LMNAPOLBOPRL1 | |
| SCHEMBL24483072 | 0.84 | SIGMAR1 (0.36) | MMP1HDAC9LMNAPOLBMEN1 | |
| SCHEMBL22709347 | 0.84 | HDAC9 (0.38) | HDAC9OPRL1TACR1TACR3 | |
| SCHEMBL24483073 | 0.84 | NOTUM (0.41) | MMP1HDAC9LMNAPOLBMEN1 | |
| SCHEMBL22709564 | 0.83 | SIGMAR1 (0.41) | MMP1LMNAMEN1MAPTKMT2A | |
| SCHEMBL24483079 | 0.83 | MEN1 (0.32) | MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL30067420 | 0.83 | MEN1 (0.32) | MEN1MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240971-A2 | KRAS G12D INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2022-11-17 | — | — | WO | disclosed |