Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30067331 | 1.00 | LTA4H (0.41) | LTA4HADRB1RENPRKCQCHRNB4 | |
| SCHEMBL1206174 | 1.00 | LTA4H (0.41) | LTA4HADRB1RENPRKCQCHRNB4 | |
| SCHEMBL5732869 | 0.86 | LTA4H (0.34) | LTA4HADRB1 | |
| SCHEMBL7241545 | 0.79 | BCHE (0.36) | LTA4HADRB1 | |
| SCHEMBL30067414 | 0.78 | LTA4H (0.33) | LTA4HADRB1 | |
| SCHEMBL7419062 | 0.77 | SLC6A1 (0.39) | LTA4HADRB1 | |
| SCHEMBL236732 | 0.77 | HRH4 (0.39) | — | |
| SCHEMBL191624 | 0.77 | HRH4 (0.39) | — | |
| SCHEMBL191625 | 0.77 | HRH4 (0.39) | — | |
| SCHEMBL26061241 | 0.76 | PRKCQ (0.31) | PRKCQSCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240971-A2 | KRAS G12D INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2022-11-17 | — | — | WO | disclosed |