Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176581 | 0.85 | CNR2 (0.41) | EPHX2HSD11B1CNR2CXCR3 | |
| SCHEMBL300693 | 0.79 | CNR1 (0.40) | CNR2POLB | |
| SCHEMBL300571 | 0.79 | CNR2 (0.42) | CNR2 | |
| SCHEMBL177011 | 0.77 | CNR2 (0.42) | EPHX2HSD11B1CNR2PDE9A | |
| SCHEMBL300688 | 0.77 | CNR2 (0.39) | EPHX2HSD11B1CNR2POLBPDE9A | |
| SCHEMBL300663 | 0.74 | POLB (0.43) | CNR2POLBFAAH | |
| SCHEMBL3466283 | 0.74 | TBXA2R (0.39) | POLBPDE9ATSHR | |
| SCHEMBL176710 | 0.74 | CNR2 (0.42) | CNR2POLB | |
| SCHEMBL176582 | 0.73 | CNR2 (0.47) | HSD11B1CNR2 | |
| SCHEMBL176740 | 0.73 | ALDH1A1 (0.45) | CNR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |