SCHEMBL30069230

SCHEMBL30069230

CC(C)Nc1cnc(C(F)(F)F)nc1Nc1cccc(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 3/20 0.41
▸ ABCG2 Q9UNQ0 2/20 0.41
▸ GRM4 Q14833 1/20 0.41
▸ CTSC P53634 6/20 0.40
▸ IDH2 P48735 2/20 0.40
▸ LMNA P02545 2/20 0.39
▸ MAPT P10636 1/20 0.39
▸ AR P10275 1/20 0.38
▸ TLR7 Q9NYK1 1/20 0.38
▸ EGFR P00533 2/20 0.38
▸ BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24754876 0.86 AURKA (0.46) SYKMAPTTLR7EGFR
SCHEMBL30177167 0.72 ABCG2 (0.46) SYKABCG2GRM4LMNAMAPT
SCHEMBL24754871 0.71 MAPT (0.49) SYKABCG2GRM4CTSCIDH2
SCHEMBL12368474 0.69 TDP1 (0.50) ABCG2GRM4LMNAEGFR
SCHEMBL28468375 0.67 ABCG2 (0.48) ABCG2GRM4CTSCIDH2LMNA
SCHEMBL14243705 0.67 KCNH3 (0.50) ABCG2CTSCIDH2LMNAMAPT
SCHEMBL12279158 0.66 BRD4 (0.56) SYKABCG2GRM4CTSCEGFR
SCHEMBL24754877 0.66 TLR7 (0.38) IDH2TLR7
SCHEMBL653263 0.66 SYK (0.53) SYKABCG2GRM4CTSCBRD4
SCHEMBL21625856 0.66 KIF11 (0.54) ABCG2GRM4IDH2MAPTAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12610730-B2 Metal complex and light emitting device CITY UNIVERSITY OF HONG KONG (HK) 2026-04-21 — — US disclosed
US-20230006152-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE CITY UNIVERSITY OF HONG KONG (HK) 2023-01-05 — — US disclosed
US-20220402955-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE CITY UNIVERSITY OF HONG KONG (HK) 2022-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230006152-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE OCIAD1, OCIAD2, OPRD1 SYK 3888/4885ABCG2 2953/4885GRM4 2352/4885
US-12610730-B2 Metal complex and light emitting device OPRD1, OCIAD2, ORC3 SYK 2503/4885ABCG2 2555/4885GRM4 999/4885
US-20220402955-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE OCIAD1, OCIAD2, OSTC SYK 3587/4885ABCG2 3580/4885GRM4 2407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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