Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938077 | 0.83 | HSD11B1 (0.33) | CA1CA2HSD11B1EPHX2 | |
| SCHEMBL2716648 | 0.83 | KMT2A (0.36) | BTKFAAH | |
| SCHEMBL22981887 | 0.83 | KMT2A (0.31) | CA1CA2PPIAEPHX2BTK | |
| SCHEMBL22981888 | 0.83 | KMT2A (0.31) | CA1CA2PPIAEPHX2BTK | |
| SCHEMBL2087505 | 0.81 | GAA (0.36) | CA2BTKFAAH | |
| SCHEMBL28189059 | 0.81 | CYP4F2 (0.33) | CA1CA2EPHX2 | |
| SCHEMBL1710210 | 0.81 | CA1 (0.36) | CA1CA2PPIAEPHX2HPGD | |
| SCHEMBL4522936 | 0.80 | HPGD (0.39) | CA1CA2EPHX2HPGD | |
| SCHEMBL4742076 | 0.80 | KMT2A (0.36) | CA1CA2HSD11B1BTK | |
| SCHEMBL15913346 | 0.80 | CA1 (0.35) | CA1CA2PPIAEPHX2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237649-A1 | EXOCYCLIC AMINO QUINAZOLINE DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |