Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003478 | 0.91 | EPHX2 (0.34) | CYP4F2CYP4A11EPHX2MEN1KMT2A | |
| SCHEMBL21777669 | 0.90 | EPHX2 (0.40) | EPHX2TSHRALOX15ATMUSP2 | |
| SCHEMBL1002483 | 0.84 | CYP4F2 (0.36) | CYP4F2CYP4A11EPHX2MEN1KMT2A | |
| SCHEMBL4463790 | 0.84 | DRD2 (0.33) | EPHX2MEN1KMT2AMAPK1USP2 | |
| SCHEMBL391708 | 0.84 | USP2 (0.45) | EPHX2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL3938077 | 0.82 | HSD11B1 (0.33) | EPHX2MEN1KMT2AMAPK1TSHR | |
| SCHEMBL1282312 | 0.82 | PPIA (0.34) | CYP4F2CYP4A11EPHX2MEN1KMT2A | |
| SCHEMBL4522936 | 0.82 | HPGD (0.39) | EPHX2MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL30069367 | 0.81 | CA1 (0.33) | EPHX2CA1CA2 | |
| SCHEMBL13737672 | 0.81 | EPHX2 (0.36) | CYP4F2CYP4A11EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102456-B | Azaquinazoline inhibitors of atypical protein kinase C | 癌症研究技术有限公司 | 2017-11-14 | — | — | CN | disclosed |