Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17761135 | 1.00 | TDP1 (0.51) | TDP1PTPN1ACP1CDC25BATM | |
| SCHEMBL25253304 | 0.79 | PTPN1 (0.44) | PTPN1ACP1CDC25BKMT2AMAPT | |
| SCHEMBL19456965 | 0.79 | TDP1 (0.44) | TDP1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL17760903 | 0.78 | PTPN1 (0.43) | PTPN1ACP1CDC25BHTTCYP1A2 | |
| SCHEMBL319410 | 0.77 | PTPN1 (0.50) | PTPN1ACP1CDC25BL3MBTL1KMT2A | |
| SCHEMBL30069860 | 0.72 | PTPN1 (0.36) | PTPN1ACP1CDC25BMEN1KMT2A | |
| SCHEMBL6078340 | 0.72 | CYP1A2 (0.43) | TDP1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL6078346 | 0.72 | CYP1A2 (0.43) | TDP1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL22409623 | 0.71 | NQO2 (0.41) | TDP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL30167913 | 0.71 | PTPN1 (0.44) | PTPN1ACP1CDC25BSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131899-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| EP-4087560-A2 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | Axial Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131899-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | SNCA, PARK7, PRNP | TDP1 452/4885PTPN1 2068/4885ACP1 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.