Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26439681 | 1.00 | PTPN1 (0.36) | PTPN1KDM4EMEN1KMT2AACP3 | |
| SCHEMBL30069765 | 0.72 | TDP1 (0.51) | PTPN1KDM4EMEN1KMT2AACP3 | |
| SCHEMBL17761135 | 0.72 | TDP1 (0.51) | PTPN1KDM4EMEN1KMT2AACP3 | |
| SCHEMBL8185296 | 0.71 | KDM4E (0.49) | KDM4EMEN1KMT2AACP3ALDH1A1 | |
| SCHEMBL30707929 | 0.71 | KDM4E (0.49) | KDM4EMEN1KMT2AACP3ALDH1A1 | |
| SCHEMBL16147542 | 0.67 | ACP3 (0.60) | KDM4EMEN1KMT2AACP3CDC25B | |
| SCHEMBL17289035 | 0.67 | KDM4E (0.44) | KDM4EMEN1KMT2AACP3ALDH1A1 | |
| SCHEMBL28705859 | 0.66 | KDM4E (0.47) | PTPN1KDM4EMEN1KMT2AACP3 | |
| SCHEMBL29081148 | 0.65 | KDM4E (0.50) | KDM4EMEN1KMT2AACP3ALDH1A1 | |
| SCHEMBL9190026 | 0.65 | PTPN1 (0.53) | PTPN1KDM4EALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087560-A2 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | Axial Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |