SCHEMBL319410

SCHEMBL319410

CC1(C)OC(=O)C(=C(O)Cc2ccccc2)C(=O)O1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.50
ACP1 P24666 3/20 0.50
CDC25B P30305 3/20 0.50
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
ALDH1A1 P00352 5/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
AKR1B1 P15121 1/20 0.41
THRB P10828 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
PRTN3 P24158 1/20 0.39
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL623728 0.87 PTPN1 (0.45) PTPN1ACP1CDC25BLMNAPOLB
SCHEMBL3297163 0.83 PTPN1 (0.55) PTPN1ACP1CDC25BLMNAALDH1A1
SCHEMBL29364967 0.80 MEN1 (0.47) PTPN1ACP1CDC25BALDH1A1SMN1; SMN2
SCHEMBL19439458 0.80 MEN1 (0.47) PTPN1ACP1CDC25BALDH1A1SMN1; SMN2
SCHEMBL25253304 0.79 PTPN1 (0.44) PTPN1ACP1CDC25BALDH1A1CYP1A2
SCHEMBL21480024 0.79 PTPN1 (0.44) PTPN1ACP1CDC25BLMNAALDH1A1
SCHEMBL17761135 0.77 TDP1 (0.51) PTPN1ACP1CDC25BLMNAPOLB
SCHEMBL30069765 0.77 TDP1 (0.51) PTPN1ACP1CDC25BLMNAPOLB
SCHEMBL1356857 0.75 PTPN1 (0.62) PTPN1ACP1CDC25BLMNAALDH1A1
SCHEMBL9188423 0.75 PTPN1 (0.46) PTPN1ACP1CDC25BPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532467-B1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-03-11 EP disclosed
US-20260013501-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-01-15 US disclosed
EP-4532467-A1 HERBICIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2025-04-09 EP disclosed
WO-2023232674-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-12-07 WO disclosed
US-8637674-B2 Pyrazole derivatives, preparation method thereof, and composition for prevention and treatment of osteoporosis containing same EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2014-01-28 US disclosed
EP-2590968-A1 CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS Novartis AG (CH) 2013-05-15 EP disclosed
US-20130109682-A1 CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS NOVARTIS AG (CH) 2013-05-02 US disclosed
US-20130109682-A1 CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS NOVARTIS AG (CH) 2013-05-02 US disclosed
US-20130109682-A1 CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS NOVARTIS AG (CH) 2013-05-02 US disclosed
US-20120232117-A1 PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTION AND TREATMENT OF OSTEOPOROSIS CONTAINING SAME EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2012-09-13 US disclosed
WO-2012004217-A1 CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS NOVARTIS AG (CH) 2012-01-12 WO disclosed
WO-2003035615-A2 TYROSINE KINASE INHIBITORS MERCK & CO., INC. (US) 2003-05-01 WO disclosed
WO-2003035616-A2 TYROSINE KINASE INHIBITORS MERCK & CO., INC. (US) 2003-05-01 WO disclosed
EP-0456073-B1 Multifunctional compounds having alpha-diazo-beta-ketoester units and sulfonic acid ester units and process for their preparation. HOECHST AG (DE) 1995-10-25 EP disclosed
US-5191069-A Photosensitive compounds with heat resistance HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-02 US disclosed
EP-0456073-A2 Multifunctional compounds having alpha-diazo-beta-ketoester units and sulfonic acid ester units and process for their preparation. HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109682-A1 CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS PIM1, GSK3A, GSK3B PTPN1 255/4885ACP1 414/4885CDC25B 370/4885
US-20260013501-A1 HERBICIDAL DERIVATIVES CBR3, CBR1, DDT PTPN1 1439/4885ACP1 2752/4885CDC25B 1713/4885
US-20120232117-A1 PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTION AND TREATMENT OF OSTEOPOROSIS CONTAINING SAME PTH1R, VDR, SOST PTPN1 1713/4885ACP1 1039/4885CDC25B 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.