Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554318 | 0.82 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL31368028 | 0.80 | MAPK1 (0.37) | HRH3CHRM2CHRM1CHRM3BTK | |
| Hydrochloric Acid SCHEMBL31368151 | 0.79 | MAPK1 (0.36) | HRH3CHRM2CHRM1CHRM3BTK | |
| SCHEMBL17883938 | 0.77 | HRH3 (0.39) | HRH3CHRM2CHRM1CHRM3BTK | |
| SCHEMBL19408614 | 0.77 | GABRR1 (0.41) | — | |
| SCHEMBL17883906 | 0.77 | HRH3 (0.39) | HRH3CHRM2CHRM1CHRM3BTK | |
| SCHEMBL3405894 | 0.77 | HRH3 (0.39) | HRH3CHRM2CHRM1CHRM3BTK | |
| SCHEMBL1298062 | 0.77 | HRH3 (0.43) | HRH3CHRM2CHRM1CHRM3BTK | |
| SCHEMBL5722384 | 0.76 | SLC6A12 (0.34) | HRH3CHRM2CHRM1CHRM3BTK | |
| Hydrochloric Acid SCHEMBL30660867 | 0.76 | HRH3 (0.38) | HRH3CHRM2CHRM1CHRM3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |