Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 3/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887029 | 0.83 | HRH3 (0.34) | HRH3GABRR1GABRR2BTKNR1H2 | |
| SCHEMBL5722453 | 0.82 | KMT2A (0.32) | HRH3BTK | |
| SCHEMBL31368028 | 0.80 | MAPK1 (0.37) | HRH3BTKNR1H2MAPK1CHRM2 | |
| Hydrochloric Acid SCHEMBL31368151 | 0.79 | MAPK1 (0.36) | HRH3BTKMAPK1CHRM2CHRM1 | |
| SCHEMBL3405894 | 0.77 | HRH3 (0.39) | HRH3BTKNR1H2MAPK1CHRM2 | |
| SCHEMBL17883938 | 0.77 | HRH3 (0.39) | HRH3BTKNR1H2MAPK1CHRM2 | |
| SCHEMBL17883906 | 0.77 | HRH3 (0.39) | HRH3BTKNR1H2MAPK1CHRM2 | |
| SCHEMBL1298062 | 0.77 | HRH3 (0.43) | HRH3BTKNR1H2MAPK1CHRM2 | |
| SCHEMBL30072791 | 0.76 | HRH3 (0.34) | HRH3BTKMAPK1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL30660867 | 0.76 | HRH3 (0.38) | HRH3BTKNR1H2MAPK1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933993-B1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2006-04-05 | — | — | EP | disclosed |
| US-6410594-B1 | VIRICIDES | BIOCRYST PHARMACEUTICALS, INC. | 2002-06-25 | — | — | US | disclosed |