SCHEMBL30073072

SCHEMBL30073072

OCCc1ccc2c(c1)COC2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
ALOX5 P09917 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
BACE1 P56817 1/20 0.45
CA2 P00918 2/20 0.40
KCNJ1 P48048 2/20 0.37
KCNH2 Q12809 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
PDK2 Q15119 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19812842 1.00 KDM4E (0.45) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL29356674 0.83 CA12 (0.35) CA2KCNJ1KCNH2CA12CA4
SCHEMBL1466786 0.83 CA12 (0.35) CA2KCNJ1KCNH2CA12CA4
SCHEMBL19367895 0.80 CNR1 (0.42) ALOX5KCNJ1KCNH2PDK2
SCHEMBL3919296 0.80 TDP1 (0.37) KCNJ1KCNH2TDP1
SCHEMBL6289134 0.80 TAAR1 (0.47) KDM4EALDH1A1GAAMAPTBACE1
Hydrochloric Acid SCHEMBL20563028 0.78 TAAR1 (0.46) KDM4EALDH1A1GAAMAPTBACE1
SCHEMBL7998432 0.78 ALDH1A1 (0.47) KDM4EALDH1A1ALOX5GAAMAPT
SCHEMBL23536305 0.75 CHRM4 (0.32) KDM4EMAPTKCNJ1KCNH2
SCHEMBL1467009 0.75 TRPA1 (0.32) KDM4EALDH1A1MAPTKCNJ1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514761-A Compounds, compositions and uses thereof 赛诺维信制药公司 2023-08-01 CN disclosed
CN-116283877-A Compounds, compositions and uses thereof 赛诺维信制药公司 2023-06-23 CN disclosed
CN-110088107-B Compounds, compositions and uses thereof 赛诺维信制药公司 2023-04-14 CN disclosed
CN-115353667-A Method and material for reducing waste 李蓁蓁 2022-11-18 CN disclosed