Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467009 | 0.83 | TRPA1 (0.32) | KCNJ1KCNH2CHRM4 | |
| SCHEMBL30073072 | 0.80 | KDM4E (0.45) | TDP1KCNJ1KCNH2 | |
| SCHEMBL19812842 | 0.80 | KDM4E (0.45) | TDP1KCNJ1KCNH2 | |
| SCHEMBL19367895 | 0.80 | CNR1 (0.42) | KCNJ1KCNH2 | |
| SCHEMBL6289134 | 0.80 | TAAR1 (0.47) | TDP1 | |
| Hydrochloric Acid SCHEMBL20563028 | 0.78 | TAAR1 (0.46) | TDP1MEN1KMT2A | |
| SCHEMBL3452332 | 0.78 | RXRB (0.41) | TDP1 | |
| SCHEMBL23536305 | 0.75 | CHRM4 (0.32) | KCNJ1KCNH2CHRM4 | |
| SCHEMBL3453086 | 0.75 | HPGD (0.40) | TDP1 | |
| SCHEMBL7699218 | 0.75 | HRH3 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006413-A1 | SUBSTITUTED PYRROLIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |