Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533796 | 0.91 | EPHX2 (0.58) | EPHX2MAPTTRPV1KMT2AEPHX1 | |
| SCHEMBL21580342 | 0.84 | EPHX2 (0.61) | EPHX2MAPTTRPV1KMT2AEPHX1 | |
| SCHEMBL26075729 | 0.81 | EGFR (0.53) | — | |
| SCHEMBL1145512 | 0.80 | EPHX1 (0.56) | EPHX2MAPTTRPV1KMT2AEPHX1 | |
| SCHEMBL11555827 | 0.79 | EPHX2 (1.00) | EPHX2MAPTTRPV1KMT2AEPHX1 | |
| SCHEMBL26074438 | 0.79 | MET (0.46) | MAPTSMN1; SMN2NPC1HPGDKDM4E | |
| SCHEMBL30074433 | 0.78 | NPC1 (0.61) | MAPTTRPV1KMT2AFAAHSMN1; SMN2 | |
| SCHEMBL2096310 | 0.78 | EPHX2 (0.76) | EPHX2MAPTTRPV1KMT2AEPHX1 | |
| SCHEMBL2096312 | 0.78 | EPHX2 (0.76) | EPHX2MAPTTRPV1KMT2AEPHX1 | |
| SCHEMBL31490975 | 0.76 | EPHX2 (0.73) | EPHX2MAPTTRPV1KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142619-B | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |