Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074396 | 0.91 | EPHX2 (0.65) | EPHX2MAPTTRPV1KMT2AKDM4E | |
| SCHEMBL21580342 | 0.82 | EPHX2 (0.61) | EPHX2MAPTTRPV1KMT2AKDM4E | |
| SCHEMBL28524761 | 0.81 | NPC1 (0.54) | MAPTTRPV1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL407809 | 0.79 | ALDH1A1 (0.56) | KDRSMN1; SMN2 | |
| SCHEMBL169453 | 0.78 | EPHX2 (0.73) | EPHX2MAPTTRPV1KMT2AKDM4E | |
| Water SCHEMBL2458178 | 0.77 | ALDH1A1 (0.55) | KDRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29453838 | 0.77 | ALDH1A1 (0.55) | KDRSMN1; SMN2 | |
| SCHEMBL28521121 | 0.77 | ALDH1A1 (0.63) | MAPTKMT2AKDM4ESMN1; SMN2FAAH | |
| Hydrochloric Acid SCHEMBL30367847 | 0.77 | EPHX2 (0.71) | EPHX2MAPTTRPV1KMT2AKDM4E | |
| SCHEMBL28528200 | 0.77 | MEN1 (0.53) | EPHX2MAPTKMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142619-B | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112142619-A | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2020-12-29 | — | — | CN | disclosed |