Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 3/20 | 0.76 |
| ▸ | VDR | P11473 | 2/20 | 0.76 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.74 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.74 |
| ▸ | CDC25A | P30304 | 3/20 | 0.70 |
| ▸ | POLA1 | P09884 | 1/20 | 0.70 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.67 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.67 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.63 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903512 | 0.99 | ABCC4 (0.78) | ABCC4VDRGRIN1GRIN2BCDC25A | |
| SCHEMBL23594716 | 0.99 | ABCC4 (0.78) | ABCC4VDRGRIN1GRIN2BCDC25A | |
| SCHEMBL8902867 | 0.99 | ABCC4 (0.78) | ABCC4VDRGRIN1GRIN2BCDC25A | |
| SCHEMBL25063600 | 0.99 | ABCC4 (0.78) | ABCC4VDRGRIN1GRIN2BCDC25A | |
| SCHEMBL13311422 | 0.90 | VDR (0.76) | ABCC4VDRGRIN1GRIN2BCDC25A | |
| SCHEMBL13347854 | 0.90 | VDR (0.76) | ABCC4VDRGRIN1GRIN2BCDC25A | |
| SCHEMBL17124639 | 0.90 | VDR (0.76) | ABCC4VDRGRIN1GRIN2BCDC25A | |
| SCHEMBL8902307 | 0.89 | ST6GAL1 (0.82) | ABCC4VDRCDC25APOLA1ST6GAL1 | |
| SCHEMBL8902302 | 0.89 | ST6GAL1 (0.82) | ABCC4VDRCDC25APOLA1ST6GAL1 | |
| Ammonia Solution, Strong SCHEMBL19179463 | 0.88 | VDR (0.98) | ABCC4VDRGRIN1GRIN2BABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638463-A1 | SALTS INCLUDING CRYSTALLINE SALTS OF 25-HYDROXY-CHOLEST-5-EN-3-SULFATE AND METHODS FOR PREPARING SAME | Durect Corporation (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4637722-A1 | 25-HYDROXY-CHOLEST-5-EN-3-SULFATE CHOLINE, FORMULATIONS THEREOF AND METHODS FOR PREPARING, AND MEDICAL USES OF SAME | Durect Corporation (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20240425545-A1 | 25-Hydroxy-Cholest-5-En-3-Sulfate Choline and Methods for Preparing, and Uses of, Same | JPMORGAN CHASE BANK, N.A. | 2024-12-26 | — | — | US | disclosed |
| WO-2024138203-A1 | 25-HYDROXY-CHOLEST-5-EN-3-SULFATE CHOLINE, FORMULATIONS THEREOF AND METHODS FOR PREPARING, AND MEDICAL USES OF SAME | DURECT CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |
| US-20230056273-A1 | CRYSTALLINE AND LIQUID CRYSTALLINE 25-HYDROXY-CHOLEST-5-EN-3-SULFATE SODIUM AND METHODS FOR PREPARING SAME | JPMORGAN CHASE BANK, N.A. | 2023-02-23 | — | — | US | disclosed |
| EP-4081028-A1 | CRYSTALLINE AND LIQUID CRYSTALLINE 25-HYDROXY-CHOLEST-5-EN-3-SULFATE SODIUM AND METHODS FOR PREPARING SAME | Durect Corporation (US) | 2022-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425545-A1 | 25-Hydroxy-Cholest-5-En-3-Sulfate Choline and Methods for Preparing, and Uses of, Same | CYP27A1, CETP, CYP46A1 | ABCC4 2890/4885VDR 390/4885GRIN1 3775/4885 |
| US-20230056273-A1 | CRYSTALLINE AND LIQUID CRYSTALLINE 25-HYDROXY-CHOLEST-5-EN-3-SULFATE SODIUM AND METHODS FOR PREPARING SAME | CYP27A1, CYP46A1, PCSK9 | ABCC4 1798/4885VDR 254/4885GRIN1 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.