Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.49 |
| ▸ | KDR | P35968 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GOT1 | P17174 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684247 | 0.81 | EGFR (0.53) | EGFRKDRLMNAALDH1A1KDM4E | |
| SCHEMBL354115 | 0.81 | EGFR (0.53) | EGFRKDRLMNAALDH1A1KDM4E | |
| SCHEMBL14993997 | 0.78 | ALDH1A1 (0.47) | EGFRKDRLMNAALDH1A1GAA | |
| SCHEMBL463374 | 0.78 | EGFR (0.47) | EGFRKDRLMNAALDH1A1GAA | |
| SCHEMBL9584154 | 0.78 | EGFR (0.50) | EGFRKDRLMNAALDH1A1GAA | |
| SCHEMBL27930312 | 0.77 | ALDH1A1 (0.46) | EGFRKDRLMNAALDH1A1GAA | |
| SCHEMBL28279906 | 0.77 | EGFR (0.49) | EGFRKDRLMNAALDH1A1KDM4E | |
| SCHEMBL29617978 | 0.76 | ALDH1A1 (0.49) | EGFRKDRLMNAALDH1A1GAA | |
| SCHEMBL9738820 | 0.76 | ALDH1A1 (0.49) | EGFRKDRLMNAALDH1A1GAA | |
| SCHEMBL28194071 | 0.73 | EGFR (0.42) | EGFRKDRLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485272-A | PLXDC2 ligands | 朗多生物制药股份有限公司 | 2022-12-16 | — | — | CN | disclosed |