Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30077253 | 1.00 | LMNA (0.42) | LMNAHPGDKCNA3FFAR4EGFR | |
| SCHEMBL30077235 | 0.83 | CYP19A1 (0.42) | LMNAHPGDCTSVCTSLHTT | |
| SCHEMBL30077236 | 0.83 | CYP19A1 (0.42) | LMNAHPGDCTSVCTSLHTT | |
| SCHEMBL30077241 | 0.83 | CYP19A1 (0.42) | LMNAHPGDCTSVCTSLHTT | |
| SCHEMBL30077217 | 0.76 | HPGD (0.53) | LMNAHPGDSMPD1HDAC1HDAC8 | |
| SCHEMBL28366085 | 0.76 | LMNA (0.48) | LMNAHPGDFFAR4SMPD1HDAC1 | |
| SCHEMBL20171129 | 0.75 | HPGD (0.54) | LMNAHPGDSMPD1HDAC1HDAC8 | |
| SCHEMBL21893208 | 0.74 | PDE4B (0.35) | LMNAHPGDSMPD1HDAC1HDAC8 | |
| SCHEMBL23667863 | 0.74 | MRGPRX4 (0.45) | HPGDKCNA3SMPD1HDAC1HDAC8 | |
| SCHEMBL31258473 | 0.74 | KDM4E (0.44) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368372-A | Heterocyclic quinazoline derivative, preparation method and application | 昆药集团股份有限公司 | 2022-11-22 | — | — | CN | disclosed |