Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754019 | 1.00 | ALOX15 (0.37) | ALOX15ALOX12HTR2AALDH1A1LMNA | |
| SCHEMBL23667871 | 0.80 | SELL (0.37) | HTR2AALDH1A1LMNAKDM4EGAA | |
| SCHEMBL1895782 | 0.79 | ALDH1A1 (0.36) | HTR2AALDH1A1LMNAMAPTDHFR | |
| SCHEMBL21634429 | 0.79 | HTR2A (0.38) | HTR2ALMNADHFR | |
| SCHEMBL23667872 | 0.79 | HTR2A (0.38) | HTR2AALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL4750485 | 0.79 | HTR2A (0.51) | HTR2AALDH1A1LMNAAKT1PKM | |
| SCHEMBL2437696 | 0.78 | FFAR4 (0.38) | HTR2ALMNADHFRFFAR4 | |
| SCHEMBL2434136 | 0.77 | LMNA (0.39) | ALDH1A1LMNAKDM4EMAPTPKM | |
| SCHEMBL11114171 | 0.76 | ALOX15 (0.35) | ALOX15ALOX12ALDH1A1AKT1 | |
| SCHEMBL2328393 | 0.76 | KMT2A (0.39) | HTR2AALDH1A1LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110964023-B | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |