Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.32 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | ABL2 | P42684 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25666758 | 1.00 | KDM4E (0.36) | KDM4EGPR3ALDH1A1GLAGAA | |
| SCHEMBL25666747 | 0.84 | KDM4E (0.38) | KDM4EGPR3ALDH1A1GLAGAA | |
| SCHEMBL25666757 | 0.81 | LMNA (0.36) | — | |
| SCHEMBL25666733 | 0.80 | KDM4E (0.39) | KDM4EGPR3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1770055 | 0.79 | KDM4E (0.41) | KDM4EGPR3NCF1ADRB2CYP1A2 | |
| SCHEMBL12406712 | 0.75 | KDM4E (0.44) | KDM4EGPR3NCF1ADRB2TGFBR1 | |
| SCHEMBL9588205 | 0.75 | GRM5 (0.40) | KDM4EGPR3ALDH1A1GLAGAA | |
| SCHEMBL25666734 | 0.70 | KDM4E (0.42) | KDM4EGPR3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL25666751 | 0.70 | KDM4E (0.39) | KDM4EGPR3NCF1ADRB2TGFBR1 | |
| SCHEMBL23405733 | 0.70 | KDM4E (0.36) | KDM4EGPR3ALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512095-B2 | BCL6 inhibitors | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512095-B2 | BCL6 inhibitors | BCL6, BCL6B, BCL3 | KDM4E 481/4885GPR3 3754/4885ALDH1A1 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.