Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511124 | 1.00 | DAO (0.49) | DAOAPPMAOBMAOAFABP3 | |
| SCHEMBL28522875 | 0.81 | APP (0.45) | DAOAPPMAOBMAOAFABP3 | |
| SCHEMBL30079980 | 0.78 | FABP3 (0.42) | DAOAPPMAOBMAOAFABP3 | |
| SCHEMBL30080032 | 0.76 | DAO (0.46) | DAOAPPMAOBFABP3FABP4 | |
| SCHEMBL29878600 | 0.75 | CASR (0.47) | APPMAOBMAOAFABP3FABP4 | |
| SCHEMBL9475495 | 0.75 | APP (0.70) | DAOAPPMAOBMAOACALM1 | |
| SCHEMBL27886911 | 0.72 | NPC1 (0.68) | PPARDRXRARXRBRXRG | |
| SCHEMBL3228582 | 0.72 | APP (0.82) | DAOAPPMAOBMAOAIDO1 | |
| SCHEMBL15211356 | 0.71 | APP (0.55) | DAOAPPMAOBMAOAFABP3 | |
| SCHEMBL5788396 | 0.70 | RXRA (0.45) | CALM1RXRARXRBRXRGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204036-B | Macrocyclic fused pyrazoles as MCL-1 inhibitors | 苏州亚盛药业有限公司 | 2022-12-27 | — | — | CN | disclosed |