SCHEMBL30080985

SCHEMBL30080985

c1ccc(-c2cccc3c2ccc2c(-c4ccccc4)cccc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.48
TNF P01375 1/20 0.48
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 2/20 0.48
BCL2L1 Q07817 1/20 0.48
CYP2A6 P11509 1/20 0.48
MAPK1 P28482 1/20 0.48
MAP4K4 O95819 1/20 0.47
CSF1R P07333 1/20 0.47
FGFR1 P11362 1/20 0.47
PDGFRA P16234 1/20 0.47
LTK P29376 1/20 0.47
KDR P35968 1/20 0.47
MAPK8 P45983 1/20 0.47
CSNK1A1 P48729 1/20 0.47
LIMK1 P53667 1/20 0.47
CDK5 Q00535 1/20 0.47
ACVR1 Q04771 1/20 0.47
TNK2 Q07912 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28322994 1.00 METAP2 (0.48) METAP2TNFALDH1A1HSD17B10HPGD
SCHEMBL2391683 0.94 ALDH1A1 (0.52) METAP2TNFALDH1A1HSD17B10HPGD
SCHEMBL443518 0.88 HPRT1 (0.64) TNFALDH1A1HSD17B10HPGDCYP2A6
SCHEMBL27631995 0.88 HPRT1 (0.64) TNFALDH1A1HSD17B10HPGDCYP2A6
SCHEMBL24078969 0.86 ALDH1A1 (0.60) METAP2TNFALDH1A1HSD17B10HPGD
SCHEMBL21124583 0.86 CYP1A2 (0.58) METAP2TNFALDH1A1CYP2A6MAP4K4
SCHEMBL27620091 0.85 HPRT1 (0.67) TNFALDH1A1HSD17B10HPGDCYP2A6
SCHEMBL3415539 0.84 ALDH1A1 (0.53) METAP2TNFALDH1A1HSD17B10HPGD
SCHEMBL29728323 0.84 ALDH1A1 (0.53) METAP2TNFALDH1A1HSD17B10HPGD
SCHEMBL13505946 0.84 HPRT1 (0.58) TNFALDH1A1HSD17B10HPGDCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115696945-A Light emitting device 株式会社半导体能源研究所 2023-02-03 CN disclosed
CN-110382502-B Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2022-11-29 CN disclosed