Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 13/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029078 | 1.00 | P2RX4 (0.40) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL27822676 | 0.85 | P2RX4 (0.51) | P2RX4LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28223433 | 0.84 | LMNA (0.49) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL28222693 | 0.81 | LMNA (0.39) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL28784154 | 0.80 | P2RX4 (0.53) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL29843231 | 0.78 | ADORA1 (0.43) | P2RX4LMNATSHRP2RX1P2RX3 | |
| SCHEMBL28223383 | 0.77 | LMNA (0.37) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7020595 | 0.77 | BCHE (0.44) | P2RX4MAPK1SCN5ASCN9A | |
| SCHEMBL7603456 | 0.75 | KMT2A (0.40) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7041384 | 0.73 | P2RX4 (0.35) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362150-A | ENPP1 inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2022-11-18 | — | — | CN | disclosed |