Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28234956 | 0.78 | P2RX4 (0.34) | KMT2APOLBALDH1A1P2RX4MEN1 | |
| SCHEMBL27762359 | 0.77 | KDM4E (0.40) | KMT2APOLBALDH1A1P2RX4KDM4E | |
| SCHEMBL9535543 | 0.77 | TGM2 (0.35) | KMT2ACYP2D6CYP2C19POLBCYP2C9 | |
| SCHEMBL22042030 | 0.77 | EPHX2 (0.40) | KMT2ACYP2D6CYP2C19POLBCYP2C9 | |
| SCHEMBL7029078 | 0.75 | P2RX4 (0.40) | ALDH1A1P2RX4LMNATSHRMAPK1 | |
| SCHEMBL30081007 | 0.75 | P2RX4 (0.40) | ALDH1A1P2RX4LMNATSHRMAPK1 | |
| SCHEMBL3076974 | 0.73 | HTR2A (0.34) | KMT2AALDH1A1MEN1LMNATSHR | |
| SCHEMBL28127957 | 0.73 | PTGS1 (0.41) | POLBALDH1A1P2RX4KDM4ETSHR | |
| SCHEMBL28097302 | 0.73 | BRD4 (0.42) | ALDH1A1 | |
| SCHEMBL3729598 | 0.72 | P2RX4 (0.41) | KMT2ACYP2D6CYP2C19POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263414-A1 | PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS | Pfizer Products Inc. (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001068055-A1 | PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2001-09-20 | — | — | WO | disclosed |