SCHEMBL3008355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15364610	0.84	TRIM24 (0.61)	ALDH1A1SMN1; SMN2TRIM24TRIM33KDM4E
	SCHEMBL7134528	0.81	ALDH1A1 (0.58)	ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL6134488	0.81	ALDH1A1 (0.52)	ALDH1A1NPC1RAB9AKDM4EHPGD
	SCHEMBL31073256	0.77	ALDH1A1 (0.48)	ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL3019038	0.77	SMN1; SMN2 (0.61)	NPC1RAB9ASMN1; SMN2KDM4ETSHR
	SCHEMBL6132953	0.77	MAPT (0.49)	ALDH1A1RAB9ASMN1; SMN2KDM4EHPGD
	SCHEMBL3018619	0.77	SMN1; SMN2 (0.61)	NPC1RAB9ASMN1; SMN2KDM4ETSHR
	SCHEMBL63894	0.77	HDAC3 (0.54)	ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL15070420	0.77	USP2 (0.69)	ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL4621744	0.77	TRIM24 (0.56)	ALDH1A1SMN1; SMN2TRIM24TRIM33KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.