⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176911 | 1.00 | — | — | |
| SCHEMBL27176907 | 0.83 | HPGDS (0.30) | — | |
| SCHEMBL30087109 | 0.83 | HPGDS (0.30) | — | |
| SCHEMBL1565246 | 0.82 | HTT (0.39) | — | |
| SCHEMBL1577309 | 0.70 | AAK1 (0.32) | — | |
| SCHEMBL24669715 | 0.68 | — | — | |
| SCHEMBL28878932 | 0.68 | AGXT (0.32) | — | |
| SCHEMBL29950898 | 0.68 | AGXT (0.32) | — | |
| SCHEMBL22866568 | 0.68 | PYCR1 (0.30) | — | |
| SCHEMBL31220060 | 0.67 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341255-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022246019-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2022-11-24 | — | — | WO | disclosed |