Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176907 | 1.00 | HPGDS (0.30) | HPGDSEGLN1 | |
| SCHEMBL30087127 | 0.83 | — | — | |
| SCHEMBL27176911 | 0.83 | — | — | |
| SCHEMBL27176822 | 0.78 | HTR7 (0.32) | HPGDS | |
| SCHEMBL23051557 | 0.70 | GAA (0.42) | — | |
| SCHEMBL29707038 | 0.70 | GAA (0.42) | — | |
| SCHEMBL23043878 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL9091041 | 0.68 | — | — | |
| SCHEMBL2160545 | 0.67 | — | — | |
| SCHEMBL29395259 | 0.65 | KDM4E (0.39) | HPGDSEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341255-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022246019-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2022-11-24 | — | — | WO | disclosed |