SCHEMBL30087635

SCHEMBL30087635

Cc1c(F)cccc1C(F)(F)C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 7/20 0.45
KCNE1 P15382 1/20 0.41
KCNQ1 P51787 1/20 0.41
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
SCN9A Q15858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CHRM3 P20309 1/20 0.36
HDAC4 P56524 1/20 0.36
TAS2R14 Q9NYV8 1/20 0.35
CYP3A4 P08684 1/20 0.34
CD38 P28907 1/20 0.34
KCNH2 Q12809 1/20 0.34
HDAC9 Q9UKV0 1/20 0.33
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30628237 0.84 SMN1; SMN2 (0.41) KCNN4KCNE1KCNQ1CES2CES1
SCHEMBL17420585 0.84 SMN1; SMN2 (0.41) KCNN4KCNE1KCNQ1CES2CES1
SCHEMBL30087649 0.81 KCNN4 (0.59) KCNN4KCNE1KCNQ1CES2CES1
SCHEMBL17420524 0.77 PIN1 (0.43) SMN1; SMN2HDAC4
SCHEMBL30087637 0.76 KCNN4 (0.41) KCNN4KCNE1KCNQ1
SCHEMBL9890797 0.75 KCNN4 (0.49) KCNN4KCNE1KCNQ1
SCHEMBL26068796 0.75 KCNN4 (0.41) KCNN4KCNE1KCNQ1
SCHEMBL173020 0.74 HSD11B1 (0.45) KCNN4SMN1; SMN2CHRM3TAS2R14
SCHEMBL10080312 0.72 CHRM3 (0.38) ESR1ESR2SMN1; SMN2CHRM3HDAC4
Ammonia Solution, Strong SCHEMBL28723095 0.72 HSD11B1 (0.44) KCNN4SMN1; SMN2CHRM3TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320192-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2025-10-16 US disclosed
US-20230242504-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2023-08-03 US disclosed
US-11535603-B1 Deuterium-enriched piperidinonyl-oxoisoindolinyl acetamides and methods of treating medical disorders using same DEUTERX, LLC (US) 2022-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242504-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME EGLN3, HPGDS, EGLN2 KCNN4 2859/4885KCNE1 3351/4885KCNQ1 1558/4885
US-20250320192-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME EGLN3, HPGDS, EGLN2 KCNN4 2859/4885KCNE1 3351/4885KCNQ1 1558/4885
US-11535603-B1 Deuterium-enriched piperidinonyl-oxoisoindolinyl acetamides and methods of treating medical disorders using same EGLN3, HPGDS, EGLN2 KCNN4 2859/4885KCNE1 3351/4885KCNQ1 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.