SCHEMBL30089277

SCHEMBL30089277

NC([C@@H](C(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
FABP5 Q01469 3/20 0.44
FABP7 O15540 2/20 0.44
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
EPHX2 P34913 1/20 0.40
MDM4 O15151 2/20 0.39
TP53 P04637 2/20 0.39
CASP3 P42574 2/20 0.39
MDM2 Q00987 1/20 0.38
CYP1A2 P05177 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7391410 0.84 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL7389338 0.84 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL7119225 0.84 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL7393490 0.84 KMT2A (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL28215432 0.83 KMT2A (0.48) KMT2AFABP5FABP7CA1CA2
SCHEMBL29036117 0.82 KMT2A (0.45) KMT2AFABP5FABP7CA1CA2
SCHEMBL2358897 0.82 MDM2 (0.43) KMT2AFABP5FABP7MDM2
SCHEMBL2311742 0.82 MDM2 (0.43) KMT2AFABP5FABP7MDM2
SCHEMBL7128599 0.82 KMT2A (0.47) KMT2AFABP5FABP7CA1CA2
SCHEMBL28888234 0.81 KMT2A (0.46) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 EP disclosed
US-11512096-B2 Seco macrolide compounds SELVITA D.O.O. (HR) 2022-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512096-B2 Seco macrolide compounds SEC61B, SEC16A, SEC61A1 KMT2A 4255/4885FABP5 3549/4885FABP7 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.